Xi'an collagen manufacturing project gains national recognition

The National Development and Reform Commission and five other central authorities have released the first batch of 136 major technology demonstration projects. The "high-end medical recombinant collagen intelligent manufacturing and clinical translation validation project", implemented by Northwest University, Giant Biogene, Xijing Hospital, and Xi'an Honghui Hospital, has been selected, becoming one of the three projects from Shaanxi province on the list.

In the past, most high-end medical collagen was extracted from animal sources, which carried risks such as residual viruses and immune rejection. Large-scale, stable production has long been a bottleneck for the entire industry.

Giant Biogene is responsible for the intelligent high-efficiency manufacturing of recombinant collagen, process enhancement validation, and the engineering scale-up of high-value products for bone repair and tissue filling in the project.  

Utilizing mature technical systems, including automated strain construction, intelligent fermentation, and continuous chromatographic purification, it has built an integrated transformation pipeline from raw materials to end products, providing hardware and process support for standardized, intelligent mass production.

Giant Biogene's company building. [Photo provided to chinadaily.com.cn]

The project's selection recognizes Giant Biogene's capabilities in research, development and manufacturing, as well as its role in connecting universities, businesses and medical institutions. The collaboration could serve as a model for similar initiatives in China.

Giant Biogene has worked with Northwest University for more than 20 years to turn scientific research into commercial products. Together, they have established several research facilities and collaborated on major research projects at the national and provincial levels.

The company will accelerate the development of its products and expand into more clinical applications. It will help foster an industrial ecosystem for intelligent manufacturing and clinical services of biomedical materials, driving its evolution from a global leader in recombinant collagen into a world-class biomaterials platform enterprise.